Police responded to the scene near Bethany Home Road and 47th Avenue shortly after 1 a.m.
Officers discovered a fight had broken out between two groups of people. One man was shot and had life-threatening injuries. He was transported to the hospital where he was later pronounced dead.
The others involved fled the area in a vehicle and are still outstanding according to the Glendale Police Department. Descriptions of the car and individuals involved were not released.
The area was still shut down as of 7:45 a.m. Monday morning while detectives were on the scene.
The investigation was ongoing. Glendale police provided no further information.
This article originally appeared on Arizona Republic: Man fatally shot during fight on Bethany Home Road in Glendale