November 3, 2025

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Can the Arizona Cardinals Bounce Back Against the Dallas Cowboys on Monday Night?

Stakes and Storylines

The Cardinals enter Monday night’s matchup at AT&T Stadium in Dallas off a 2-5 record, having dropped five straight after a 2-0 start. Meanwhile, the Cowboys sit at 3-4-1, also struggling to find consistency despite boasting one of the NFL’s top offenses. (nfl.com)
Both teams are desperate to turn the tide — the Cardinals to end the skid, the Cowboys to avoid slipping further. The prime-time spotlight adds urgency.

Injuries & Key Player Status

Injuries tilt the situation in interesting ways:

Cardinals:

  • Kyler Murray (QB) is listed as questionable with a foot injury; the team has confirmed he will not start and veteran Jacoby Brissett will take the snaps. (New York Post)
  • CB Will Johnson (groin) — questionable. (Arizona Cardinals)
  • S Kitan Crawford (ankle) — questionable. (Arizona Cardinals)
  • LB B.J. Ojulari (knee) — out. (Arizona Cardinals)

Cowboys:

  • S Donovan Wilson (elbow/shoulder) — out. (SI)
  • LB DeMarvion Overshown (knee) — out. (SI)
  • CB Shavon Revel (knee) — out. (SI)
  • S Juanyeh Thomas (migraine) — questionable. (SI)

Odds & Implied Outcomes

According to recent handicapping guides:

  • The Cardinals are +3 underdogs (i.e. Cowboys favored by 3). (statsalt.com)
  • The over/under for total points is around 53.5. (statsalt.com)

Why the Cardinals Could Pull It Off

  • The Cowboys’ defense has been wildly inconsistent, ranking near the bottom in yards allowed and big plays surrendered. (statsalt.com)
  • The Cardinals, with their bye week to rest and prepare, may have the edge in freshness.
  • Even with the QB question, Brissett has shown enough in his recent starts to at least keep the offense moving.

Why Dallas Should Win

  • Their offense remains elite: high yardage, potent passing attack, and weaponry at wide receiver. (statsalt.com)
  • Home-field advantage in prime time adds pressure that the Cardinals (in slump mode) may struggle under.
  • Dallas has a relatively healthier offensive unit compared to Arizona’s questions at key positions.

Final Prediction

This one could be a tight, high-scoring affair. If the Cardinals start quickly and catch Dallas off balance with injuries, they have a shot. But the safe money is on the Cowboys — take Dallas as the 3-point favorite, and consider the over 53.5 total points given both offenses and the defensive vulnerabilities.
If you lean Cardinals, the +3 looks fair and may even offer value.